Heat olive oil in a large skillet over medium heat. Season meat with salt, pepper, garlic powder, and Italian seasoning, then add meat in an even layer to pan.
Cook meat until slightly browned on both sides, about 2-3 minutes per side. If needed, drain some of the fat from the meat and return to skillet.
Add sliced onions and mushrooms to same skillet and sauté until tender, about 5 minutes. Add more salt and pepper, if needed.
Add College Inn® Simple Starter Hearty Beef Sauce and Worcestershire sauce. Stir to combine.
Bring mixture to a boil, then cover and simmer for about 10 minutes.